Alcaloides pirrolizidinicos em plantas brasileiras de interesse alimentar e medicinal : identificação e toxicologia

AUTOR(ES)
DATA DE PUBLICAÇÃO

2000

RESUMO

Plants containing pyrrolizidine alkaloids (PA s) are consumed as medicinal herbs or as foods (salads, juices).in India, Afganistan, America, Russia and Brazil. But nowadays those species are known as carcinogenic for laboratory animaIs. There are concrete evidence that the effects of a single dose of PA can cause chronic liver disease and cirrhosis. PA s are esters l-methilhydroxylpyrrolizines, composed by an aminoalcohol (necine base) and an acid (necic acid). More than 200 structures had been isolated from species of Senecio and Eupatorium (Asteraceae) , (Boraginaceae) . In this work, preliminary qualitative analysis using GC-MS was Crotalaria (Leguminosae) and Heliotropium performed in 28 Senecio species and 87 of Eupatorium. Senecio showed three types of PAs satured...Note: The complete abstract is available with the full electronic digital thesis or dissertations

ASSUNTO(S)

ervas alcaloides plantas medicinais

Documentos Relacionados