Alpha Interferon Augments Cidofovir's Antiviral and Antiproliferative Activities
AUTOR(ES)
Johnson, Jeffrey A.
FONTE
American Society for Microbiology
RESUMO
The antiviral and antiproliferative activities of alpha 2a interferon (IFN-α2a) and cidofovir in human papillomavirus type 16 (HPV-16)-transformed keratinocytes were evaluated. The compounds in combination were more effective than comparable levels of either drug alone. Evaluation of effective drug ratios revealed a synergistic cooperation between IFN-α2a and cidofovir in inhibiting the proliferation of HPV-infected cells.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=155837Documentos Relacionados
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