Amino Acid Transport in Mycoplasma
AUTOR(ES)
Razin, S.
RESUMO
The uptake of l-histidine by Mycoplasma fermentans and l-methionine by M. hominis was found to be dependent on temperature and pH and to follow saturation kinetics. Several metabolic inhibitors inhibited this uptake. The transport system for l-methionine was highly specific. The l-histidine transport system was less specific, and the uptake was competitively inhibited by l-arginine and l-lysine. l-Histidine accumulated in the intracellular pool of M. fermentans at a concentration about 200 times that found in the medium. Efflux of accumulated l-histidine was demonstrated at 37 C, but not at 0 C. The rate of efflux was greatly accelerated by addition of l-histidine to the medium. The findings indicate that the Mycoplasma cell membrane contains specific transport systems resembling the permease systems of other microorganisms.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=252196Documentos Relacionados
- Amino Acid Transport in Pseudomonas aeruginosa
- Amino Acid Transport in Mycobacterium smegmatis
- Amino Acid Transport in a Polyaromatic Amino Acid Auxotroph of Saccharomyces cerevisiae
- Role of transport systems in amino acid metabolism: leucine toxicity and the branched-chain amino acid transport systems.
- Neutral Amino Acid Transport in Pseudomonas fluorescens
