An Extension of a Model for the Evolution of Multigene Families by Unequal Crossing over
AUTOR(ES)
Ohta, Tomoko
RESUMO
Evolution of a multigene family is studied from the standpoint of population genetics. It is assumed that the multigene family is undergoing continuous interchromosomal unequal crossing over, mutation and random frequency drift. The equilibrium properties of the probability of gene identity (clonality) are investigated, using two measures: identity probability within and between chromosomes. The measures represent homogeneity of genes within a family in one chromosome and similarity of gene families between two homologous chromosomes. The means, the variances and the covariance of these two measures of identity probability are obtained by using the diffusion equation method. It is shown that the means and the variances are generally smaller than those predicted in the previous model assuming intrachromosomal (sister chromatid) unequal crossing over (Ohta 1978a,b).
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1216852Documentos Relacionados
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