An ultrastructural study of the testis and epididymis of the rat after treatment with prostaglandins E2 and F2 alpha (PGE2 and PGF2 alpha).

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RESUMO

Intratesticular injections of PGE2 and PGF2 alpha caused damage to germ cells and exfoliation of part of the damaged germinal epithelium into the epididymis. Membrane-bound granular bodies and localized swellings were also seen in some of the myoid cells in experimental animals. However, the Sertoli cells and Leydig cells remained unaffected.

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