Analysis of T antigen and viral DNA in mouse cells transformed by K virus, a nononcogenic murine papovavirus.
AUTOR(ES)
Kanda, T
RESUMO
A tumorigenic line of mouse cells transformed by the nononcogenic murine K papovavirus was established and characterized. Tumor-bearing animals produced antibody specific for K virus-transformed cells; the K virus T antiserum did not react with polyomavirus-transformed cells. Immunoprecipitation of the T antigen in the transformed cells revealed large T antigen (molecular weight 84,000). About 10 to 15 copies of K virus DNA were found to be integrated in the cellular DNA.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=255761Documentos Relacionados
- Genome analysis of MG virus, a human papovavirus.
- T antigen of BK papovavirus in infected and transformed cells.
- Persistent BK papovavirus infection of transformed human fetal brain cells. I. Episomal viral DNA in cloned lines deficient in T-antigen expression.
- Instability of integrated viral DNA in mouse cells transformed by simian virus 40.
- Intracellular Viral RNA Species in Mouse Cells Nonproductively Transformed by the Murine Sarcoma Virus
