Analysis of Virus-Specific CD4+ T Cells during Long-Term Gammaherpesvirus Infection

AUTOR(ES)

Flaño, Emilio

FONTE

American Society for Microbiology

RESUMO

Major histocompatibility complex class II-mediated antigen presentation after intranasal infection with murine gammaherpesvirus 68 differs in mediastinal lymph nodes and spleen. Evidence that virus-specific CD4+ T cells were being stimulated was found as late as 6 to 8 months after infection, and cells specific for the viral gp15067–83 and ORF11168–180 peptides were maintained as a fairly stable proportion of the total response.

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