Anatomy of herpes simplex virus DNA. II. Size, composition, and arrangement of inverted terminal repetitions.
AUTOR(ES)
Wadsworth, S
RESUMO
Electron microscope studies on self-annealed intact single strands and on partially denatured molecules show that herpes simplex virus 1 DNA consists of two unequal regions, each bounded by inverted redundant sequences. Thus the region L (70 percent of the contour length of the DNA) separates the left terminal region a1b from its inverted repeat b'a'1, each of which comprises 6 percent of the DNA. The region S (9.4 percent of DNA) separates the right terminal region cas (4.3 percent of the DNA) from its inverted repeat a'sc'. The regions of the two termini which are inverted and repeated itnernally differ in topology. Thus, cas is guanine plus cytosine rich, whereas only the terminal 1 percent of the a1b region, designated as subregion a1, is guanine plus cytosine rich.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=354616Documentos Relacionados
- Size, Composition, and Structure of the Deoxyribonucleic Acid of Herpes Simplex Virus Subtypes 1 and 2
- Size, subunit composition, and secondary structure of the Friend virus genome.
- Anatomy of herpes simplex virus DNA. V. Terminally repetitive sequences.
- Anatomy of Herpes Simplex Virus DNA. VIII. Properties of the Replicating DNA
- Arrangement of sequences in the inverted terminal repetition of adenovirus 18 DNA.
