Anti-beta-endorphin immunoglobulin G in humans.

AUTOR(ES)

Roy, B F

RESUMO

Human IgG specific for beta-endorphin was identified by enzyme-linked immunoabsorbent assay and isolated by affinity chromatography. From a sample of 27 subjects, three individuals with major depression demonstrated plasma IgG highly reactive with human beta-endorphin, while four other subjects (two with depression and two randomly selected blood donors) had intermediate reactivity. The recognition site for beta-endorphin was retained by F(ab')2 fragments.

Documentos Relacionados

• Anti-Fab antibodies in humans. Predominance of minor immunoglobulin G subclasses in rheumatoid arthritis.
• Antigen(s) responsible for immunoglobulin G responses specific for the acute stage of Toxoplasma infection in humans.
• Binding specificity of antiidiotypic autoantibodies to anti-DNA antibodies in humans.
• Cytokine regulation of antigen-driven immunoglobulin production in filarial parasite infections in humans.
• Processing of the precursor to corticotropin and beta-lipotropin in humans.