Anti-Toxoplasma Activities of Antiretroviral Drugs and Interactions with Pyrimethamine and Sulfadiazine In Vitro

AUTOR(ES)

Derouin, Francis

FONTE

American Society for Microbiology

RESUMO

The anti-Toxoplasma activities of nine antiretroviral drugs were examined in vitro. Nucleoside analogs had no effect on parasite growth, whereas ritonavir and nelfinavir were inhibitory for Toxoplasma, with 50% inhibitory concentrations of 5.4 and 4.0 μg/ml, respectively. None of the antiviral drugs affected the anti-Toxoplasma activity of pyrimethamine or sulfadiazine.

Documentos Relacionados

• Anti-Toxoplasma effects of dapsone alone and combined with pyrimethamine.
• Anti-Toxoplasma Activities of 24 Quinolones and Fluoroquinolones In Vitro: Prediction of Activity by Molecular Topology and Virtual Computational Techniques
• Anti-Toxoplasma gondii Activities and Structure-Activity Relationships of Novel Fluoroquinolones Related to Trovafloxacin
• Detection of anti-Toxoplasma immunoglobulin M in pregnant women.
• Analytical validation of anti-toxoplasma IgG immunoassays