Antibiotic-Resistant Cell-Detaching Escherichia coli Strains from Nigerian Children
AUTOR(ES)
Okeke, Iruka N.
FONTE
American Society for Microbiology
RESUMO
The properties of 23 cell-detaching Escherichia coli strains that were isolated from stool specimens in Nigeria are described. Common properties of the strains included the presence of genes encoding α-hemolysin (100%), pyelonephritis-associated pili (100%), and cytotoxic necrotizing factor 1 (70%) as well as lactose negativity (70%) and multiple antibiotic resistance (74%). Antibiotic resistance was shown in most cases to be transferable and associated with the presence of class 1 integrons. Phenotypic properties and pulsed-field gel electrophoresis analysis demonstrated that the majority of the strains, particularly multiply resistant, lactose-negative O4:H40 strains, were closely related. Multiply-resistant cell-detaching E. coli strains may represent an important reservoir for antibiotic resistance genes.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=120082Documentos Relacionados
- Detection of HeLa cell-detaching activity and alpha-hemolysin production in enteroaggregative Escherichia coli strains isolated from feces of Brazilian children.
- Isolation of a cell-detaching factor of Trichomonas vaginalis.
- Association between alpha-hemolysin production and HeLa cell-detaching activity in fecal isolates of Escherichia coli.
- Hemolysin-Positive Enteroaggregative and Cell-Detaching Escherichia coli Strains Cause Oncosis of Human Monocyte-Derived Macrophages and Apoptosis of Murine J774 Cells
- Does prolonged exposure to antibiotic-resistant bacteria increase the rate of antibiotic-resistant infection?