ANTIBODIES TO RIBONUCLEIC ACID IN SYSTEMIC LUPUS ERYTHEMATOSUS*
AUTOR(ES)
Schur, Peter H.
RESUMO
Sera of 16 of 89 patients with systemic lupus erythematosus contained precipitating antibodies to RNA. These antibodies were found infrequently in patients with rheumatoid arthritis and Sjögren's syndrome, and not at all in patients with juvenile rheumatoid arthritis, myeloma, nor in normal individuals. These studies present evidence for the presence of antibodies to double-stranded RNA (both synthetic and viral). The fact that mammalian RNA's are probably single-stranded nucleotides suggests that these anti-RNA antibodies are directed primarily to a foreign, double-stranded RNA antigen.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=223435Documentos Relacionados
- Antibodies to Native and Denatured Deoxyribonucleic Acid in Systemic Lupus Erythematosus*
- Studies of Cryoproteins in Systemic Lupus Erythematosus*
- BILATERAL BAND-SHAPED DEEP KERATITIS AND IRIDOCYCLITIS IN SYSTEMIC LUPUS ERYTHEMATOSUS*
- Antibodies to protein P in systemic lupus erythematosus.
- Relation of antivimentin antibodies to anticardiolipin antibodies in systemic lupus erythematosus.
