Antibody to the RNA-Dependent DNA Polymerase of Mammalian C-Type RNA Tumor Viruses
AUTOR(ES)
Aaronson, Stuart A.
RESUMO
Sera from rats bearing transplantable tumors induced by murine C-type tumor viruses contain an inhibitor of the activity of the viral RNA-dependent DNA polymerase. The inhibitor is shown to be an immunoglobulin (IgG) directed against the enzyme. Antiserum made in rabbits against partially purified murine leukemia virus polymerase also inhibits the polymerases of other mammalian C-type RNA-containing tumor viruses. Thus, the polymerases from different mammalian tumor viruses are antigenically related.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=389081Documentos Relacionados
- Specificity of the DNA Product of the C-Type Virus RNA-Dependent DNA Polymerase
- Specificity of the DNA Product of RNA-Dependent DNA Polymerase in Type C Viruses: II. Quantitative Analysis*
- An Oligonucleotide Affinity Column for RNA-Dependent DNA Polymerase from RNA Tumor Viruses
- RNA-Dependent DNA Polymerase Activity of RNA Tumor Viruses I. Directing Influence of DNA in the Reaction
- RNA-Dependent DNA Polymerase Activity of RNA Tumor Viruses II. Directing Influence of RNA in the Reaction
