Antifungal susceptibility profile of Trichosporon isolates: correlation between CLSI and etest methodologies
AUTOR(ES)
Lemes, Raquel M.L., Lyon, Juliana P., Moreira, Leonardo M., Resende, Maria Aparecida de
FONTE
Brazilian Journal of Microbiology
DATA DE PUBLICAÇÃO
2010-06
RESUMO
The aim of the present study was to evaluate the antifungal susceptibility profile of Trichosporon species isolated from different sources employing the Clinical and Laboratory Standards Institute (CLSI) method and E-test method. Thirty-four isolates of Trichosporon spp. and six CBS reference samples were tested for their susceptibility to Amphotericin B, 5-flucytosine, Fluconazole, Itraconazole, Voriconazole and Terbinafine. All species showed high Minimun Inhibitory Concentrations (MIC) for Itraconazole and susceptibility to Fluconazole, The comparison among the results obtained by the CLSI method and E-test revealed larger discrepancies among 5-flucytosine and Itraconazole. The present work provides epidemiological data that could influence therapeutic choices. Furthermore, the comparison between different methodologies could help to analyze results obtained by different laboratories.
Documentos Relacionados
- Correlation between microdilution, Etest, and disk diffusion methods for antifungal susceptibility testing of fluconazole against Candida sp. blood isolates
- Correlation between E-Test, Disk Diffusion, and Microdilution Methods for Antifungal Susceptibility Testing of Fluconazole and Voriconazole
- Clinical Case of Endocarditis due to Trichosporon inkin and Antifungal Susceptibility Profile of the Organism
- Multisite reproducibility of the Etest MIC method for antifungal susceptibility testing of yeast isolates.
- Susceptibility in vitro of isolates of Stenotrophomonas maltophilia: comparison of three methodologies (disc diffusion, e-test and agar-dilution)