Anucleate cell production by Escherichia coli delta hns mutant lacking a histone-like protein, H-NS.

AUTOR(ES)

Kaidow, A

RESUMO

Normal-sized anucleate cells were observed in the cultures of a delta hns mutant strain. Even in nucleate cells, some populations showed irregular intracellular localization of the nucleoids. The delta hns mutant showed reduced ploidy, although initiation of chromosome replication was essentially synchronous as defined by flow cytometric analysis. These results indicate that the delta hns mutant is defective in the mechanisms of chromosome partitioning and chromosome replication.

Documentos Relacionados

• Role of Histone-Like Protein H-NS in Multidrug Resistance of Escherichia coli
• Regulation of lysyl-tRNA synthetase expression by histone-like protein H-NS of Escherichia coli.
• Rapid site-specific DNA inversion in Escherichia coli mutants lacking the histonelike protein H-NS.
• A role for histone-like protein H1 (H-NS) in the regulation of hemolysin expression by Serratia marcescens
• Coordinated and differential expression of histone-like proteins in Escherichia coli: regulation and function of the H-NS analog StpA.