Aquaporin-2 in the “-omics” Era*
AUTOR(ES)
Hoffert, Jason D.
FONTE
American Society for Biochemistry and Molecular Biology
RESUMO
Vasopressin controls renal water excretion largely through actions to regulate the water channel aquaporin-2 in collecting duct principal cells. Our knowledge of the mechanisms involved has increased markedly in recent years with the advent of methods for large-scale systems-level profiling such as protein mass spectrometry, yeast two-hybrid analysis, and oligonucleotide microarrays. Here we review this progress.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2685649Documentos Relacionados
- Upregulation of aquaporin-2 water channel expression in chronic heart failure rat.
- Renal Dose Dopamine Mediates the Level of Aquaporin-2 Water Channel (Aqp2) in Broiler Chickens
- Lithium-induced downregulation of aquaporin-2 water channel expression in rat kidney medulla.
- Defective aquaporin-2 trafficking in nephrogenic diabetes insipidus and correction by chemical chaperones.
- Three Families with Autosomal Dominant Nephrogenic Diabetes Insipidus Caused by Aquaporin-2 Mutations in the C-Terminus
