Assessing the Reproducibility of Asthma Candidate Gene Associations, Using Genome-wide Data
AUTOR(ES)
Rogers, Angela J.
FONTE
American Thoracic Society
RESUMO
Rationale: Association studies have implicated many genes in asthma pathogenesis, with replicated associations between single-nucleotide polymorphisms (SNPs) and asthma reported for more than 30 genes. Genome-wide genotyping enables simultaneous evaluation of most of this variation, and facilitates more comprehensive analysis of other common genetic variation around these candidate genes for association with asthma.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2695495Documentos Relacionados
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