Association between pathogens from tracheal aspirate and oral biofilm of patients on mechanical ventilation
AUTOR(ES)
SOUZA, Luana Carneiro Diniz, MOTA, Vanise Barros Rodrigues da, CARVALHO, Alícia Valéria dos Santos Zaranza de, CORRÊA, Rita da Graça Carvalhal Frazão, LIBÉRIO, Silvana Amado, LOPES, Fernanda Ferreira
FONTE
Braz. oral res.
DATA DE PUBLICAÇÃO
05/06/2017
RESUMO
Abstract The aim of this study was to detect possible associations between respiratory pathogens from tracheal aspirate and oral biofilm samples in intubated patients in an intensive care unit (ICU), and to identify the most common respiratory pathogens in oral biofilm, particularly in patients that developed ventilator-associated pneumonia (VAP). Two oral biofilm samples were collected from the tongue of intubated patients (at admission and after 48 hours) and analyzed by culture with the Antibiotic Sensitivity Test. The results from the tongue biofilm samples were compared with the tracheal secretions samples. A total of 59.37% of patients exhibited the same species of pathogens in their tracheal aspirate and oral biofilm, of which 8 (42.1%) developed VAP, 10 (52.63%) did not develop pneumonia and one (5.26%) had aspiration pneumonia. There was a statistically significant association between presence of microorganisms in the tracheal and mouth samples for the following pathogens: Klebsiella pneumoniae, Candida albicans, Pseudomonas aeruginosa, Enterobacter gergoviae, Streptococcus spp and Serratia marcescens (p < 0.05). Pathogens that are present in tracheal aspirates of intubated patients can be detected in their oral cavity, especially in those who developed VAP or aspiration pneumonia. Thus, the results indicate that an improved oral care in these patients could decrease ICU pneumonia rates.
Documentos Relacionados
- Isolation of Branhamella catarrhalis from sputum and tracheal aspirate.
- Evaluation of systemic inflammation in patients being weaned from mechanical ventilation
- Measurement of pressure-volume curves in patients on mechanical ventilation: methods and significance
- Assisted ventilation. 4. Weaning from mechanical ventilation.
- Evaluation of ICU patients requiring mechanical ventilation