Autoregulation of iclR, the gene encoding the repressor of the glyoxylate bypass operon.
AUTOR(ES)
Gui, L
RESUMO
The aceBAK operon was partially induced by a multicopy plasmid which carried the promoter region of the gene which encodes its repressor, iclR. Gel shift and DNase I analyses demonstrated that IclR binds to its own promoter. Disruption of iclR increased the expression of an iclR::lacZ operon fusion. Although aceBAK and iclR are both regulated by IclR, aceBAK expression responds to the carbon source, while expression of iclR does not.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=177660Documentos Relacionados
- Regulation of the glyoxylate bypass operon: cloning and characterization of iclR.
- Sequence analysis of the iclR gene encoding the repressor of the acetate operon in Salmonella typhimurium.
- Regulation of the acetate operon in Escherichia coli: purification and functional characterization of the IclR repressor.
- The binding site of the IclR repressor protein overlaps the promoter of aceBAK.
- Regulated expression of a repressor protein: FadR activates iclR.