Baseline Susceptibility of Primary Human Immunodeficiency Virus Type 1 to Entry Inhibitors
AUTOR(ES)
Labrosse, Béatrice
FONTE
American Society for Microbiology
RESUMO
Human immunodeficiency virus type 1 plasma viruses from 29 entry inhibitor-naive patients were characterized for their susceptibilities to T-20, AMD3100, and RANTES. A strikingly wide range of susceptibilities to T-20 was observed that was influenced by coreceptor usage but not by the susceptibilities of the viruses to inhibitors that target the chemokine receptors or by polymorphisms in the gp41 N helix.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=140831Documentos Relacionados
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