bcr/abl and src but not myc and ras replace v-abl in lymphoid transformation.

AUTOR(ES)

Engelman, A

RESUMO

Lymphoid cells transformed by temperature-sensitive Abelson virus die at the nonpermissive temperature. This property was exploited to show that bcr/abl and v-src but not myc and ras can replace the transforming signal of v-abl, a result suggesting that the former but not the latter oncogenes transform lymphoid cells via a similar pathway.

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