Biochemical aspects of motor neurone disease—Madras pattern
AUTOR(ES)
Valmikinathan, K.
RESUMO
A detailed study of four cases of MND-Madras has shown a significantly low plasma citrate level in these subjects. Comparison with other related groups of neurological disorders indicates the citrate/pyruvate ratio to be of diagnostic value in MND-Madras. This seems to suggest that the pathophysiology of MND-Madras may centre round altered citrate metabolism.
