Borna disease virus, a negative-strand RNA virus, transcribes in the nucleus of infected cells.
AUTOR(ES)
Briese, T
RESUMO
Borna disease virus, an unclassified infectious agent, causes immune-mediated neurologic disease in a wide variety of animal hosts and may be involved in pathogenesis of selected neuropsychiatric diseases in man. Initial reports suggested that Borna disease virus is a single-stranded RNA virus. We describe here a method for isolation of viral particles that has allowed definitive identification of the genome as containing a negative-polarity RNA. Further, we show that the viral mRNAs are transcribed in the nucleus.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=50576Documentos Relacionados
- RNA splicing in Borna disease virus, a nonsegmented, negative-strand RNA virus.
- Identification of alternative splicing and negative splicing activity of a nonsegmented negative-strand RNA virus, Borna disease virus
- Identification of signal sequences that control transcription of borna disease virus, a nonsegmented, negative-strand RNA virus.
- Transcription elongation factor of respiratory syncytial virus, a nonsegmented negative-strand RNA virus.
- Sindbis virus nsP1 functions in negative-strand RNA synthesis.