Calculation of antibody affinity in homogeneous and heterogeneous systems.

AUTOR(ES)

Chalquest, R R

RESUMO

Antibody affinity is an important determinant of all antibody-antigen reactions. A new computer program, AFCRV, was developed to calculate binding constants with data from a radioimmunoassay on most microcomputers in the laboratory by using constant-ratio dilution curves. Evaluation of a homogeneous or heterogeneous antibody in the presence of a single antigen can be accomplished.

Documentos Relacionados

• Theoretical calculation of relative binding affinity in host-guest systems.
• Listeria monocytogenes Scott A transports glucose by high-affinity and low-affinity glucose transport systems.
• Characterization of the Rhizobium (Sinorhizobium) meliloti high- and low-affinity phosphate uptake systems.
• Kinetics of a bacterial culture growth: validity of the affinity rule in biological systems.
• Detection of rotavirus in stool specimens with monoclonal and polyclonal antibody-based assay systems.