Cefmenoxime penetration into gallbladder bile and tissue.
AUTOR(ES)
Smith, B R
RESUMO
Cefmenoxime concentrations in gallbladder bile and tissue were assessed in patients undergoing cholecystectomy. A 0.5-g intravenous dose produced mean concentrations in bile of 54.1 micrograms/ml at 62.9 min and 56.3 micrograms/ml at 194 min after the dose was given. A 1.0-g intravenous dose produced concentrations in bile of 117.9 micrograms/ml at 53 min and 169.7 micrograms/ml of 194 min after the dose was given. Mean concentrations in tissue ranged from 6.1 to 17.9 micrograms/g. Biliary tree penetration was dose and time dependent. Therapeutic concentrations were achieved.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=185014Documentos Relacionados
- Enoxacin penetration into human prostatic tissue.
- Intraoperative concentrations of ofloxacin in serum, bile fluid, and gallbladder wall tissue.
- Piperacillin distribution into bile, gallbladder wall, abdominal skeletal muscle, and adipose tissue in surgical patients.
- Ceftazidime concentration in gallbladder tissue and excretion in bile.
- Concentration of norfloxacin in human gallbladder tissue and bile after single-dose oral administration.
