Cell-Mediated Immune Responses of Preleukemic AKR Mice
AUTOR(ES)
Martig, Robert J.
RESUMO
Splenic lymphocytes from preleukemic AKR mice are capable of participating in various cell-mediated immune responses. Spleen cells from AKR mice aged 1 to 10 months produced a significant graft-versus-host reaction when injected into 8-day-old AKR × C57Bl/6 F1 hybrids. Splenic lymphocytes from similarly aged mice were also capable of responding to allogenic stimulation in a mixed lymphocyte reaction. AKR mice aged 1 to 10 months developed a contact sensitivity response to picryl chloride. It was concluded that mice of this high-leukemic strain have a competent cell-mediated immune system and there is no depression of immunity during the preleukemic period.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=423054Documentos Relacionados
- Human cell-mediated immune responses to chlamydial antigens.
- Induction and expression of cell-mediated immune responses in inbred mice infected with Coccidioides immitis.
- Impairment of cell-mediated immune responses by infection with Mycobacterium lepraemurium.
- Cell-mediated immune response to influenza virus infections in mice.
- Modulation by gamma interferon of antiviral cell-mediated immune responses in vivo.
