Cell Separation on Affinity Columns: The Isolation of Immunospecific Precursor Cells from Unimmunized Mice

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RESUMO

We have used affinity columns to isolate from the spleens of unimmunized mice a population of lymphocytes that specifically bind a lactoside hapten. These cells are able to initiate an antibody response to azophenyl-β-lactoside when transferred to appropriate irradiated recipients.

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