Cell wall modification resulting from in vitro induction of L-phase variants of Nocardia asteroides.
AUTOR(ES)
Beaman, B L
RESUMO
The chemical composition of the cell walls of several L-form revertants derived from Nocardia asteroides 10905 was determined at different stages of growth. It was observed that each L-form revertant had a cell well that differed from that of the parental strain when grown under identical conditions. In some strains the peptidolipid and mycolic acid components were affected the most, whereas in other strains the fatty acid, sugar, and mycolic acid moieties were altered. Shifts in mycolic acid size were prominent, whereas the basic peptidoglycan structure appeared to be affected the least. Both the method used to induce the L-form of N. asteroides 10905 and the length of time these organisms were maintained in the wall-less state affected the degree of cell wall modification during the reversion process. Thus, removal of the cell wall appeared to potentiate and select for mutational alterations within the cell envelope of N. asteroides, and these changes resulted in altered cellular and colonial morphology.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=216245Documentos Relacionados
- Induction of L-phase variants of Nocardia caviae within intact murine lungs.
- Viability of L-Phase Variants After Centrifugation
- Prosthetic valve endocarditis resulting from Nocardia asteroides.
- INDUCTION BY ANTIBIOTICS AND COMPARATIVE SENSITIVITY OF L-PHASE VARIANTS OF STAPHYLOCOCCUS AUREUS
- Peptidoglycan synthesis in L-phase variants of Bacillus licheniformis and Bacillus subtilis.
