Challenges in pulmonary fibrosis · 5: The NSIP/UIP debate
AUTOR(ES)
du Bois, Roland
FONTE
BMJ Group
RESUMO
Among the idiopathic interstitial pneumonias, the two entities—idiopathic pulmonary fibrosis (IPF) characterised by the presence of the usual interstitial pneumonia pattern of histopathology (IPF/UIP) and non‐specific interstitial pneumonia (NSIP; same nomenclature for the histopathological pattern and idiopathic disease)—have provoked considerable debate. IPF/UIP and NSIP closely mimic each other clinically but NSIP has a far better outcome. However, it remains unclear if NSIP is a truly separate and distinct entity. The histopathological pattern of NSIP can be found in a wide variety of clinical and radiological contexts. This review addresses these and other uncertainties regarding NSIP and UIP.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2117119Documentos Relacionados
- Challenges in pulmonary fibrosis · 2 : Bronchiolocentric fibrosis
- Challenges in pulmonary fibrosis · 3: Cystic lung disease
- Challenges in pulmonary fibrosis · 4: Smoking‐induced diffuse interstitial lung diseases
- Capítulo 5: Caminhos trilhados
- Constitutive activation of 5-lipoxygenase in the lungs of patients with idiopathic pulmonary fibrosis.