Characterization of Ferrochelatase (hemH) Mutations in Haemophilus influenzae

AUTOR(ES)

Schlör, Stefan

FONTE

American Society for Microbiology

RESUMO

Haemophilus influenzae lacks most of the biosynthetic enzymes for hemin synthesis. However, the organism has retained ferrochelatase activity, which we identified to be encoded by a hemH-homologous gene. In this report we characterize the growth physiology conferred by hemH mutations under infection and laboratory conditions.

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