Characterization of the recognition site and diagnostic potential of an enterovirus group-reactive monoclonal antibody.

AUTOR(ES)

Samuelson, A

RESUMO

The epitope for a monoclonal antibody reactive against different enteroviruses was characterized. The epitope could be located to residues 40 to 48 of VP1, and the most-essential residues for monoclonal antibody binding coincided with those conserved among the majority of known enteroviruses, indicating a high diagnostic potential.

Documentos Relacionados

• Identification of a group-reactive epitope of group B rotaviruses recognized by monoclonal antibody and application to the development of a sensitive immunoassay for viral characterization.
• Use of a group-reactive and other monoclonal antibodies in an enzyme immunodot assay for identification and presumptive serotyping of aquatic birnaviruses.
• Complete nucleotide sequence of the group-reactive antigen VP7 gene of bluetongue virus.
• Selective Binding of Blood Group-Reactive Salivary Mucins by Streptococcus mutans and Other Oral Organisms
• Characterization of the cDNA of a broadly reactive neutralizing human anti-gp120 monoclonal antibody.