Chemical transformation of eremofortin C into PR toxin.

AUTOR(ES)

Li, S Y

RESUMO

The natural products of both eremofortin C (EC) and PR toxin are secondary metabolites of Penicillium roqueforti. Because the chemical structures of EC and PR toxin are closely related to each other and differ only by a hydroxyl functional group in EC and an aldehyde functional group in PR toxin at the C-12 position, the chemical transformation of EC into PR toxin was investigated. Oxidation with a chromic anhydride-pyridine complex was found to be the most satisfactory method.

Documentos Relacionados

• Factors affecting the production of eremofortin C and PR toxin in Penicillium roqueforti.
• Isolation and Some Properties of the Enzyme That Transforms Eremofortin C to PR Toxin
• Production, purification, and chemical characterization of Staphylococcus aureus exfoliative toxin.
• Investigations into the relationship between structure and function of diphtheria toxin.
• Cloning and expression of functional fragment C of tetanus toxin.