Chemoreflex modulation by hypoxia and hypercapnia through submaximal exercise in heart failure patients / "Modulação do quimioreflexo por hipóxia e hipercapnia durante exercício submáximo na insuficiência cardíaca"

AUTOR(ES)
DATA DE PUBLICAÇÃO

2005

RESUMO

Heart failure(HF) dyspnea is complex with potential enrolment of central(CC) and peripheric chemoreceptors(PC).We investigated CC and CP behavior through submaximal exercise in 15 HF patients and 7 normal subjects in treadmill 6-minute cardiopulmonary walking tests:isocapnic hypoxia(HPO), hypercapnia hyperoxic(HCP) and room air.HPO increased:ventilation(VE) with acute ventilatory response(AVR), heart rate (HR) and O2 uptake and reduced dead space, distance walked (DW) and systemic blood pressure(SBP).The HPC improved VE above HPO level with AVR. PC have greater action on HR and SBP than CC,despite their largest sympathetic activation. PC have faster impulse on VE although be lowest than CC

ASSUNTO(S)

exercÍcio heart failure congestive/physiopathology quimiorreceptores insuficiÊncia cardÍaca congestiva/fisiopatologia exercise chemoreceptors

ACESSO AO ARTIGO

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