CHOP: visualization of ‘wobbling’ and isolation of highly conserved regions from aligned DNA sequences
AUTOR(ES)
Ohtsuka, Masato
FONTE
Oxford University Press
RESUMO
The web software CHOP was developed to visualize the ‘wobbling’ in the third codon position of aligned DNA sequences. The simple features of this tool allow users to easily find regions suspected of containing coding sequences (CDSs). The program also allows visualization of the nucleotide diversity between two genomic or gene sequences by graphically plotting the percentage identity between the two sequences. CHOP can also isolate highly conserved regions within both CDSs and non-CDSs. Highly conserved regions within CDSs include the regions with lower rates of synonymous substitution in which nucleotide sequences are expected to be under strong selective pressure. CHOP is available at http://bunsei2.med.u-tokai.ac.jp:8080/~ohtsuka/cds_finding.html.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=441586Documentos Relacionados
- CHOP: parsing proteins into structural domains
- PCR Use of Highly Conserved DNA Regions for Identification of Sinorhizobium meliloti
- RevTrans: multiple alignment of coding DNA from aligned amino acid sequences
- Human Ah receptor cDNA: analysis for highly conserved sequences.
- Highly conserved repetitive DNA sequences are present at human centromeres.
