Ciprofloxacin disk susceptibility tests: interpretive zone size standards for 5-microgram disks.

AUTOR(ES)

Barry, A L

RESUMO

Evaluations of 5-microgram ciprofloxacin disk diffusion susceptibility tests were performed independently by seven different investigators. The results of the separate tests were combined to increase the number of resistant strains in the challenge set of microorganisms. Based on data with 2,652 isolates, the following interpretive breakpoints are tentatively proposed for use in ongoing clinical trials of ciprofloxacin: less than or equal to 15 mm, resistant (MIC greater than 2.0 micrograms/ml); 16 to 20 mm, intermediate (1.0 less than MIC less than or equal to 2.0 micrograms/ml); and greater than or equal to 21 mm, susceptible (MIC less than or equal to 1.0 micrograms/ml). Disk tests with Streptococcus spp. and with Pseudomonas maltophilia were not reliable; other microorganisms were accurately categorized by the disk diffusion test.

Documentos Relacionados

• Interpretive criteria for disk diffusion tests using 5-microgram cefdinir disks with rapidly growing clinical isolates.
• Interpretive standards and quality control guidelines for imipenem susceptibility tests with 10-micrograms disks.
• Interpretive standards and quality control limits for susceptibility tests with ampicillin-sulbactam combination disks.
• Preliminary interpretive susceptibility testing criteria for FK-037 with 30-microgram disks.
• Tentative interpretive criteria for the diffusion susceptibility test using 30-microgram netilmicin disks.