Cloning and expression analysis of full length mouse cDNA sequences encoding the transformation associated protein p53.
AUTOR(ES)
Jenkins, J R
RESUMO
We have cloned and sequenced overlapping cDNA fragments which together encode the entire mouse protein p53. Using these cDNA's we have reconstructed the full length coding region for the protein, and have analysed its coding potential by expression in vitro, both as a full length sequence and as a subfragment contained in a fusion protein. The predicted amino acid sequence contains no obvious homologies to any known oncogenes but includes a possible tyrosine kinase acceptor site.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=320018Documentos Relacionados
- Cloning and expression of full-length cDNA encoding human vitamin D receptor.
- Nucleotide sequence of a cDNA encoding the monkey cellular phosphoprotein p53.
- Cloning and sequencing analysis of a full-length cDNA encoding a G protein alpha subunit, SGA1, from soybean.
- Molecular cloning and in vitro expression of a cDNA clone for human cellular tumor antigen p53.
- Cloning and expression of cDNA encoding mouse tyrosinase.