Cluster of Candida parapsilosis primary bloodstream infection in a neonatal intensive care unit

AUTOR(ES)

Silva, Carmem Lúcia P. da, Santos, Rosana M. R. dos, Colombo, Arnaldo Lopes

FONTE

Brazilian Journal of Infectious Diseases

DATA DE PUBLICAÇÃO

2001-02

RESUMO

Candida parapsilosis is an increasingly important bloodstream pathogen in neonatal intensive care units (NICU). We investigated a cluster of bloodstream infections in a NICU to determine whether nosocomial transmission occurred. During a 3-day period, 3 premature infants hospitalized in the same unit presented with sepsis caused by C. parapsilosis. Electrophoretic karyotype of the organisms was performed by using pulsed field gel electrophoresis in a countour-clamped homogeneous electric field system. The isolate from 1 newborn could not be typed, and the isolates from the remaining 2 infants had identical patterns. All 3 cases are described. We conclude that nosocomial transmission of C. parapsilosis occurred and that neonates under intensive care may represent a risk group for this pathogen.

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