Comparative antibacterial activity of hexachlorophane in different formulations used for skin disinfection

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RESUMO

Two formulations of hexachlorophane have been compared for their antibacterial effects in respect of skin disinfection. It was found that the activity of hexachlorophane is dependent upon its vehicle of formulation. A 2·5% soap gel possesses broad-spectrum bactericidal activity with remarkable speed of kill, whereas a 3% detergent formulation has no bactericidal action against Gram-negative bacteria and only a very slow action against Gram-positive bacteria.

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