Comparative virulence of Scedosporium species in animal models
AUTOR(ES)
Nweze, EI, Okafor, JI
FONTE
Brazilian Journal of Infectious Diseases
DATA DE PUBLICAÇÃO
2010-06
RESUMO
Scedosporium species are an emerging opportunist group of fungi that have been found to cause infections in both immunocompetent and non-immunocompetent individuals. The infections are not regularly distributed among different countries of the world either because of improper identification or other geographical reasons. Strange as it may, disseminated systemic infections have only been reported in some specific countries. We used a mouse model of disseminated infection to assess if strains from Nigeria were virulent and compared it to a few other strains from other countries. S. apiospermum isolated from Nigeria were clearly less virulent than those obtained elsewhere. This may be the reason why this group of fungi has not been associated with specific clinical problems in Nigeria in pa'rticular and Africa in general.
Documentos Relacionados
- Comparative Analysis of Plant and Animal Models for Characterization of Burkholderia cepacia Virulence
- Animal models for pathogenic Neisseria species.
- Scedosporium apiospermum, Scedosporium aurantiacum, Scedosporium minutisporum and Lomentospora prolificans: a comparative study of surface molecules produced by conidial and germinated conidial cells
- Use of tissue culture and animal models to identify virulence-associated traits of Haemophilus ducreyi.
- Comparison of guinea pig and protozoan models for determining virulence of Legionella species.