Comparison of two methods of genetic exchange in determination of the genetic locus of the structural gene for Pseudomonas aeruginosa elastase.
AUTOR(ES)
Howe, T R
RESUMO
A mutation, lasA1, that results in the synthesis of enzymatically inactive elastase protein was mapped by R68.45 plasmid-mediated conjugation and transposon-facilitated recombination to ca. 75 min on the Pseudomonas aeruginosa PAO chromosome. Since immunologically cross-reactive material is produced, the mutation presumably arose within the elastase structural gene.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=215050Documentos Relacionados
- Structural gene and complete amino acid sequence of Pseudomonas aeruginosa IFO 3455 elastase.
- Comparison of the Vibrio cholerae hemagglutinin/protease and the Pseudomonas aeruginosa elastase.
- Synthesis, processing, and transport of Pseudomonas aeruginosa elastase.
- Degradation of basement membranes by Pseudomonas aeruginosa elastase.
- Pseudomonas aeruginosa elastase does not inactivate alpha 1-proteinase inhibitor in the presence of leukocyte elastase.