Complement components and IgE in patients with asthma and aspirin idiosyncrasy.
AUTOR(ES)
Delaney, J C
RESUMO
Levels of circulating IgE, total haemolytic complement, and components C4 and C3 were measured in 16 asthmatics with aspirin idiosyncrasy and in control subjects. IgE levels were mostly within normal limits. No differences were found between the complement profiles-in particular the C4 levels-in the two groups. As low levels of C4 have been found in patients with intrinsic asthma, these results would suggest a fundamental difference between asthmatics with aspirin idiosyncrasy and others with intrinsic asthma.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=470453Documentos Relacionados
- Relationship between omalizumab pharmacokinetics, IgE pharmacodynamics and symptoms in patients with severe persistent allergic (IgE-mediated) asthma
- IgE in asthma and atopy: cellular and molecular connections
- Circulating human IgG autoanti-IgE antibodies in asthma patients block the binding of IgE to its high affinity receptor
- Serum immunoglobulin (IgE) levels in asthma.
- The metabolism of IgE in patients with immunodeficiency states and neoplastic conditions.