Complete structural characterisation of the human aryl hydrocarbon receptor gene
AUTOR(ES)
Bennett, P
RESUMO
Aims—To clone and characterise the complete structural gene for the human aryl hydrocarbon receptor (AhR). This gene, located on chromosome 7, encodes a cytosolic receptor protein which, upon activation by various xenobiotic ligands, translocates to the nucleus, where it acts as a specific transcription factor.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=408011Documentos Relacionados
- Polymorphism of the aryl-hydrocarbon receptor gene in intron 10 of human cancers
- Caenorhabditis elegans orthologs of the aryl hydrocarbon receptor and its heterodimerization partner the aryl hydrocarbon receptor nuclear translocator
- Ligand Selectivity and Gene Regulation by the Human Aryl Hydrocarbon Receptor in Transgenic MiceS⃞
- Recruitment of the NCoA/SRC-1/p160 Family of Transcriptional Coactivators by the Aryl Hydrocarbon Receptor/Aryl Hydrocarbon Receptor Nuclear Translocator Complex
- Analysis of the Complex Relationship between Nuclear Export and Aryl Hydrocarbon Receptor-Mediated Gene Regulation