Computational discovery of sense-antisense transcription in the human and mouse genomes

AUTOR(ES)

Shendure, Jay

FONTE

BioMed Central

RESUMO

Overlapping but oppositely oriented transcripts have the potential to form sense-antisense perfect double-stranded (ds) RNA duplexes. A bioinformatics approach has identified over 217 candidate overlapping transcriptional units, bringing the total number of predicted and validated examples of overlapping but oppositely oriented transcripts to over 300.

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