Concentration of ciprofloxacin in human prostatic tissue after oral administration.
AUTOR(ES)
Dan, M
RESUMO
Concomitant concentrations of ciprofloxacin in serum, urine, and prostatic tissue were determined in 15 patients after single oral doses of 750 mg. Levels in tissue ranged from 0.6 to 4.18 micrograms/g, and therapeutic concentrations were demonstrable for up to 9 h after administration. The mean ratio of tissue to serum concentration was 0.93 +/- 0.08 (standard error).
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=176441Documentos Relacionados
- Concentration of norfloxacin in human gallbladder tissue and bile after single-dose oral administration.
- Pharmacokinetics of ciprofloxacin after oral and parenteral administration.
- Pharmacokinetics of ofloxacin after parenteral and oral administration.
- Comparative pharmacokinetics and tissue penetration of sulbactam and ampicillin after concurrent intravenous administration.
- Tolerance and disposition of cefpimizole in normal human volunteers after intramuscular administration.
