Contribution of Clumping Factor B to Pathogenesis of Experimental Endocarditis due to Staphylococcus aureus
AUTOR(ES)
Entenza, J. M.
FONTE
American Society for Microbiology
RESUMO
Staphylococcus aureus Newman with an insertion mutation in clfB, the gene encoding clumping factor B, only marginally decreased infection rate (P > 0.05) in rats with experimental endocarditis. In contrast, clfB complementation on a multicopy plasmid significantly increased infectivity (P < 0.05) over the deleted mutants. Although clfB could affect endovascular infection, its importance in experimental endocarditis was limited.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=101814Documentos Relacionados
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