Contribution of the cell-surface-associated enzyme in the Zimmermann-Rosselet assay of outer membrane permeability of beta-lactam antibiotics.
AUTOR(ES)
Liu, W
RESUMO
Analysis of beta-lactam hydrolysis by intact cells of several strains of enteric bacteria suggests that a significant fraction of beta-lactamase molecules is present at a location directly accessible for the substrates in the medium. We propose a method to correct for the error introduced by these "surface-exposed" enzymes in the Zimmermann-Rosselet assay of outer membrane permeability.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=244962Documentos Relacionados
- Continuous infusion of beta-lactam antibiotics.
- Comparative activities of 13 beta-lactam antibiotics.
- Penetration of the outer membrane of Pseudomonas aeruginosa by synergistic combinations of beta-lactam and aminoglycoside antibiotics.
- Function of the Outer Membrane of Escherichia coli as a Permeability Barrier to Beta-Lactam Antibiotics
- Response of Legionella pneumophila to beta-lactam antibiotics.
