Cooperative chiral order in the B-Z transition in random sequences of DNA.
AUTOR(ES)
Selinger, J V
RESUMO
We present a theory for cooperative chiral order in the transition between right-handed B-DNA and left-handed Z-DNA. This theory, based on the random-field Ising model, predicts the characteristic length scale of Z-DNA segments. This length scale depends on whether the DNA is a homopolymer or a random sequence: it is approximately 4000 nucleotides in a homopolymer but only approximately 25 nucleotides in a random sequence. These theoretical results are consistent with experiments on DNA homopolymers and random sequences.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1180993Documentos Relacionados
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