Correlation between changes in systolic time intervals and left ventricular end-diastolic diameter after preload reduction. Non-invasive monitoring of pharmacological intervention.
AUTOR(ES)
Buch, J
RESUMO
In order to measure the effect of a decrease in preload on systolic time intervals and left ventricular end-diastolic diameter (LVEDD) measured by echocardiography, eight healthy young subjects were given 40 mg frusemide intravenously. The pre-ejection period index (PEPI) increased and the left ventricular end-diastolic diameter decreased. A correlation between delta PEPI and delta LVEDD was shown. Using changes in systolic time intervals in the evaluation of changes in contractility it is important to correct for changes in preload. For normal subjects it is suggested that the relation between delta PEPI and delta LVEDD as a percentage of the mean values should be used for this correction. A method is suggested for estimating the changes in pre-ejection period index induced by changes in left ventricular end-diastolic diameter.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=482463Documentos Relacionados
- Measurement of right ventricular end-systolic and end-diastolic volumes by the thermodilution technique.
- Relation of P-S4 interval to left ventricular end-diastolic pressure.
- Non-invasive measurement of left ventricular function in coronary artery disease. Comparison of first pass radionuclide ventriculography, M-mode echocardiography, and systolic time intervals.
- Pulmonary artery and left heart end-diastolic pressure relations.
- Studies of correlation between progression of coronary artery disease, as assessed by coronary arteriography, left ventricular end-diastolic pressure, ejection fraction, and employability.