Death begets failure in the heart

AUTOR(ES)

Foo, Roger S.-Y.

FONTE

American Society for Clinical Investigation

RESUMO

Recently, low — but abnormal — rates of cardiomyocyte apoptosis have been observed in failing human hearts. Genetic and pharmacological studies suggest that this cell death is causally linked to heart failure in rodent models. Herein, we review these data and discuss potential therapeutic implications.

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