Degradation of DNA in cells and extracts of the obligately anaerobic bacterium Roseburia cecicola upon exposure to air.
AUTOR(ES)
Martin, J H
RESUMO
High-molecular-weight chromosomal DNA from Roseburia cecicola, an oxygen-intolerant anaerobe, could be isolated only when the bacterial cells were kept under anaerobic conditions up to the time of cell lysis. When the cells were exposed to oxygen before lysis, the chromosomal DNA degraded. Likewise, linear but not covalently closed circular DNAs degraded in cell extracts of the organism that were exposed to atmospheres containing O2 but not in extracts that were maintained in a reduced state. Covalently closed circular DNAs were nicked but not degraded in the oxidized extracts.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=202708Documentos Relacionados
- Colonization of gnotobiotic mice by Roseburia cecicola, a motile, obligately anaerobic bacterium from murine ceca.
- Characterization of an activity from the strict anaerobe Roseburia cecicola that degrades DNA when exposed to air.
- Cloning, nucleotide sequence, and taxonomic implications of the flagellin gene of Roseburia cecicola.
- PHYSIOLOGICAL STUDY OF AN OBLIGATELY ANAEROBIC UREOLYTIC BACTERIUM
- Synthesis of guanosine tetra- and pentaphosphates by the obligately anaerobic bacterium Bacteroides thetaiotaomicron in response to molecular oxygen.
